Comparative Study of Different Doses of Dexmedetomidine As An Adjuvant To Intrathecal Hyperbaric Bupivacaine In Lower Limb Orthopaedic Surgeries

Abstract

Background: This study is aimed to assess the effect of Intrathecal administration of different doses of Dexmedetomidine with hyperbaric Bupivacaine.

Methods: A prospective randomized double blind study was conducted with 150 consenting patients of ASA grade I and II, scheduled for lower limb Orthopaedic surgeries. Using the lottery method, the patients were randomly allotted into 3 groups, 50 patients in each group. Group A, Group B & Group C. 

Results: Post-operative VAS and total analgesic requirement in 24 hours were minimal in group C as compare to B group. All the patients achieved Bromage scale 3 motor blocks and there was dose dependent prolongation of motor block in B and C groups. Similarly regression of motor block to Bromage 0 was significantly prolonged in group C than B and A group. Complete recovery of sensory and motor functions was observed in all the patients.

Conclusion: Supplementation of spinal Bupivacaine with Dexmedetomidine significantly prolonged both sensory and motor block compared with intrathecal Bupivacaine alone.

Keywords: Dexmedetomidine, Bupivacaine, Intrathecal