TO STUDY EFFICACY OF AMISULPRIDE IN TREATMENT OF SCHIZOPHRENIA.

Abstract

The study was performed at the Department of Pharmacology in collaboration with Department of Psychiatry, NSCB Medical College, Jabalpur. The maximum numbers of patients in were in reproductive age group that is in between 20 to 49 years. The mean age in Amisulpride group was 33.26(±10.23) years while in Olanzapine group it was 31.25 (±12.22) years.

Schizophrenia was more common (80%) in younger (20-49years) age group. In our study the male /female ratio was 1.7. Our study supports the notion that Schizophrenia is more common in Married and Urban population. Only one patient from Olanzapine  Group suffered  Extrapyramidal  symptoms of  moderate severity requiring  withdrawal from study.2  patients  from Olanzapine group and 1 patient from Amisulpride group  had Tremors and Akathesia  of mild severity. There was no emergence of Extrapyramidal symptoms in rest of the patients (p>.05)

Keywords: Efficacy, Amisulpride, Olanzapine & Schizophrenia.